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Kossiakoff, Anthony

One or more keywords matched the following items that are connected to Kossiakoff, Anthony

Item Type	Name
Concept	Amino Acid Sequence
Academic Article	Variability of conformations at crystal contacts in BPTI represent true low-energy structures: correspondence among lattice packing and molecular dynamics structures.
Academic Article	Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Academic Article	Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor.
Academic Article	X-ray structure of human relaxin at 1.5 A. Comparison to insulin and implications for receptor binding determinants.
Academic Article	Probing intermolecular backbone H-bonding in serine proteinase-protein inhibitor complexes.
Academic Article	The 2.0 A structure of bovine interferon-gamma; assessment of the structural differences between species.
Academic Article	Deciphering the role of the electrostatic interactions involving Gly70 in eglin C by total chemical protein synthesis.
Academic Article	Shotgun alanine scanning shows that growth hormone can bind productively to its receptor through a drastically minimized interface.
Academic Article	The first semi-synthetic serine protease made by native chemical ligation.
Academic Article	Crystal structure and site 1 binding energetics of human placental lactogen.
Academic Article	Synthetic antibodies for specific recognition and crystallization of structured RNA.
Academic Article	X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers.
Academic Article	The 1.38 A crystal structure of DmsD protein from Salmonella typhimurium, a proofreading chaperone on the Tat pathway.
Academic Article	X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid beta-protein precursor.
Academic Article	Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope.
Academic Article	Total chemical synthesis and X-ray crystal structure of a protein diastereomer: [D-Gln 35]ubiquitin.
Academic Article	Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution.
Academic Article	The X-ray structure of a growth hormone-prolactin receptor complex.
Academic Article	Crystal structure of full-length KcsA in its closed conformation.
Academic Article	Use of the neutron diffraction--H/D exchange technique to determine the conformational dynamics of trypsin.
Academic Article	Neutron diffraction identifies His 57 as the catalytic base in trypsin.
Academic Article	X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling.
Academic Article	The crystal structure of affinity-matured human growth hormone at 2 A resolution.
Academic Article	Comparison of the intermediate complexes of human growth hormone bound to the human growth hormone and prolactin receptors.
Academic Article	Molecular recognition in biological systems: from activation to inhibition.
Academic Article	High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries.
Academic Article	Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods.
Academic Article	Mechanisms of zymogen activation.
Academic Article	Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold.
Academic Article	An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells.
Academic Article	Characterization of engineered actin binding proteins that control filament assembly and structure.
Academic Article	Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments.
Academic Article	Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
Academic Article	Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
Academic Article	A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction.
Academic Article	Architecture of the fungal nuclear pore inner ring complex.
Academic Article	Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin.
Academic Article	Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM.
Academic Article	Engineered Ultra-High Affinity Synthetic Antibodies for SARS-CoV-2 Neutralization and Detection.
Academic Article	Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Academic Article	Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels.

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Amino Acid Sequence